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Scientific research on Misai Kucing has begun since 1970 (Van der Venn: Pharmaceutisch Weekblad), (Schmidt and Bos, Walter de Gruyter & Co., Berlin/New York: Volatile of Orthosiphon Stamineus Benth, Progress in Essential Oil Research), (Massuda T: A Highly Oxygenerated Diterpene From Orthosiphon Stamineus, Tetrahedron Letter). In Malaysia, research institutes such as the Institute of Medical Research and the Kuala Lumpur Hospital of the Malaysian Health Ministry are participating actively in conducting clinical study to prove the efficacy of Misai Kucing in treating kidney stone disease. The School of Pharmaceutical Sciences,Universiti Sains Malaysia contributes to the scientific research and development of Misai Kucing by conducting the extraction, quality control, standardization, pharmacological and formulation research.
Orthosiphon Trial : A study by the Clinical Research Centre, Ministry of Health Malaysia to determine the efficacy of Orthosiphon Stamineus (Misai Kucing) (200 mg/day) compared to placebo for a treatment period of 24 months in patients with Idiopathic hypocitraturic, hyperuricosuria, hyperoxaluric calcium nephropathies and hyperuricaemic nephropathies with respect to urinary tract stone formation rate. Mega Project - Medical Research : Universiti Sains Malaysia have received two grants totalling RM12.5 million from the Ministry of Science, Technology and Environment Malaysia (MOSTE) under the Intensification of Research in Priority Areas (IRPA) Programme of the 8th Malaysian Plan (RM8) to conduct two researches, headed by Prof Madya Zhari Ismail and Prof Madya Rusli Ismail.
Prof Zhari from the School of Pharmaceutical Science has been given the task to carry out a Clinical Study of Standardised Misai Kucing (Orthosiphon Stamineus, Benth) for Kidney Stone Disease and upscaling from Laboratory to Pilot Scale Production.
The objective of this research is to develop a cure for several diseases such as gout, arthritis, rheumatism, inflammatory conditions and even for kidney stones. The best part that is the cure is produced from a local herb called Misai Kucing.
In Japan, in a study on the antihypertensive substance in the leaves of Misai Kucing by the Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, exhibited a continuous decrease in systolic blood pressure, a decrease in cardiac output and diuretic action in conscious stroke-prone hypertensive rats.
In Indonesia, the National Cardiovascular Center Harapan Kita (Pusat Jantung Nasional Harapan Kita) has conducted a clinical observation on the effectiveness of the consumption of Misai Kucing traditional medicine by the wide population in treating hypertension.
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Disclaimer: The information presented here is for educational purposes only.
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